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Four different groups of children were used in this study. Children primed with either aP or wP vaccine at 2, 3, 4, and 11 months of age received an aP booster vaccine at 4 years of age. The aP-primed group received a high-dose vaccine and the wP-primed group received a low-dose vaccine. The groups of children were studied pre-booster vaccination and at 10 days post-booster vaccination. Numbers of individuals used varied in the different stimulations, as indicated.
