Profiling of cytokines and chemokines. (A) Concentrations of the cytokines IFN-γ, IL-10, IL-2, IL-4, IL-6, TNF, and IL-17A in various groups. (B) Concentrations of the chemokines IL-8/CXCL8, IP-10/CXCL10, MCP-1/CCL2, MIG/CXCL9, and RANTES/CCL5 in various groups. *, P value (two tailed) of ≤0.05, as determined by a Mann-Whitney or Wilcoxon signed-rank test.