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. 2015 Jun;28(6):771–781. doi: 10.5713/ajas.14.0008

Figure 3.

Figure 3

Location of the association signal and pairwise linkage disequilibrium (LD) surrounding the most associated SNPs on chromosome 16:14.18–17.79 Mb. LD pattern is depicted using stage 1 data. Association signals are shown for all single-nucleotide polymorphisms (SNPs) genotyped in stage 1 samples (green circles, n = 240); significant SNPs in combined dataset of stage 2 (red diamond, n = 1,156). This region has six nearest genes related to significant SNPs. The most associated SNP, BIEC2-330691, lies in the gene GXYLT2 and are in small LD. Four SNPs lies in the gene PDZRN3 and are in almost complete LD. GXYLT2, glucoside xylosyltransferase 2; PDZRN3, PDZ domain-containing ring finger 3.