Table 1.
List of SNPs with a p-value of <0.000632911 (equivalent to p = 0.1 after Bonferroni correction) based on the linear regression model of stage 2 data (n = 1,156)
| Chr | BP | Neareat gene (Ensemble gene ID) |
SNP type | Minor allele | Major allele | Stage 1 | Stage 2 | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
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|
|
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| p-value | MAF | SNP effect | p-value | MAF | SNP effect | |||||||
| BIEC2_906777 | 5 | 40747218 | - (ENSECAG00000019204) |
InterGenic | A | G | 1.63.E-04 | 0.356 | 0.278 | 8.38.E-05 | 0.330 | 0.141 |
| BIEC2_1026019 | 8 | 5906904 | INPP5J (ENSECAG00000006664) |
InterGenic | A | G | 1.64.E-05 | 0.159 | −0.4315 | 1.73.E-04 | 0.190 | −0.163 |
| BIEC2_1026200 | 8 | 6126833 | OSBP2 (ENSECAG00000015443) |
InterGenic | G | A | 1.06.E-05 | 0.107 | −0.5102 | 1.28.E-05 | 0.142 | −0.215 |
| BIEC2_1029757 | 8 | 11590300 | MVK (ENSECAG00000023067) |
InterGenic | C | A | 1.75.E-05 | 0.119 | −0.4715 | 8.85.E-06 | 0.137 | −0.219 |
| BIEC2_330101 | 16 | 14185461 | - | InterGenic | C | A | 1.39.E-04 | 0.254 | 0.3328 | 4.29.E-06 | 0.216 | 0.195 |
| BIEC2_330360 | 16 | 15550375 | - | InterGenic | A | G | 8.12.E-04 | 0.388 | 0.2536 | 2.00.E-06 | 0.371 | 0.167 |
| BIEC2_330495 | 16 | 16289366 | CNTN3 (ENSECAG00000013575) |
Genic | A | G | 3.81.E-04 | 0.298 | 0.2847 | 1.91.E-04 | 0.271 | 0.143 |
| BIEC2_330509 | 16 | 16334663 | InterGenic | G | A | 4.43.E-04 | 0.297 | 0.2818 | 8.79.E-05 | 0.274 | 0.150 | |
| BIEC2_330558 | 16 | 16948655 | PDZRN3 (ENSECAG00000014864) |
Genic | G | A | 6.02.E-04 | 0.377 | 0.2565 | 2.28.E-05 | 0.362 | 0.150 |
| BIEC2_330572 | 16 | 16993987 | Genic | A | G | 7.93.E-04 | 0.367 | 0.2484 | 4.53.E-05 | 0.358 | 0.145 | |
| BIEC2_330575 | 16 | 16999220 | Genic | A | G | 2.32.E-04 | 0.354 | 0.2734 | 1.73.E-04 | 0.339 | 0.134 | |
| BIEC2_330578 | 16 | 17001997 | Genic | G | A | 6.02.E-04 | 0.377 | 0.2565 | 1.92.E-05 | 0.363 | 0.152 | |
| BIEC2_330677 | 16 | 17421511 | PPP4R2 (ENSECAG00000000689) |
Genic | A | G | 6.13.E-04 | 0.377 | 0.2562 | 2.66.E-05 | 0.359 | 0.149 |
| BIEC2_330691 | 16 | 17546589 | GXYLT2 (ENSECAG00000008483) |
Genic | G | A | 7.05.E-04 | 0.371 | 0.2611 | 8.94.E-08 | 0.355 | 0.191 |
| BIEC2_330725 | 16 | 17763943 | SHQ1 (ENSECAG00000015673) |
InterGenic | G | A | 4.49.E-04 | 0.325 | 0.2802 | 9.40.E-07 | 0.316 | 0.180 |
| BIEC2_330739 | 16 | 17790340 | InterGenic | G | A | 6.71.E-04 | 0.315 | 0.2672 | 2.97.E-06 | 0.310 | 0.172 | |
| BIEC2_527753 | 20 | 29897398 | VARS2 (ENSECAG00000018202) |
Genic | A | G | 4.60.E-04 | 0.219 | 0.3011 | 1.32.E-05 | 0.172 | 0.195 |
| BIEC2_527879 | 20 | 30126579 | - (ENSECAG00000015285) |
InterGenic | A | G | 4.60.E-04 | 0.219 | 0.3011 | 6.86.E-06 | 0.172 | 0.202 |
| BIEC2_529755 | 20 | 32127869 | - (ENSECAG00000017401) |
InterGenic | A | C | 5.23.E-04 | 0.256 | 0.2969 | 3.80.E-05 | 0.210 | 0.171 |
| BIEC2_529760 | 20 | 32131071 | InterGenic | C | A | 2.39.E-04 | 0.296 | 0.2909 | 4.09.E-06 | 0.239 | 0.180 | |
| BIEC2_554645 | 21 | 18154976 | ARL15 (ENSECAG00000014970) |
Genic | A | G | 1.98.E-05 | 0.218 | −0.3696 | 7.44.E-06 | 0.213 | −0.188 |
| BIEC2_554739 | 21 | 18348602 | InterGenic | C | A | 9.53.E-05 | 0.265 | −0.3267 | 1.94.E-04 | 0.256 | −0.146 | |
| BIEC2_568963 | 21 | 47502588 | - | InterGenic | A | G | 4.70.E-04 | 0.471 | −0.2539 | 1.98.E-05 | 0.474 | −0.149 |
| BIEC2_569862 | 21 | 48967346 | CCT5 (ENSECAG00000019192) |
InterGenic | G | A | 2.59.E-04 | 0.373 | −0.2739 | 2.57.E-06 | 0.381 | −0.165 |
| BIEC2_570062 | 21 | 49384234 | Genic | A | C | 1.30.E-04 | 0.404 | 0.2819 | 2.12.E-04 | 0.386 | 0.127 | |
| BIEC2_570485 | 21 | 49894191 | TAS2R1 (ENSECAG00000005160) |
InterGenic | A | G | 3.40.E-04 | 0.215 | 0.3012 | 3.48.E-04 | 0.209 | 0.148 |
| BIEC2_732151 | 28 | 17405077 | - | InterGenic | A | C | 7.52.E-05 | 0.290 | 0.3151 | 4.42.E-04 | 0.274 | 0.134 |
| BIEC2_814518 | 30 | 3869336 | RGS7 (ENSECAG00000009422) |
InterGenic | A | G | 2.33.E-05 | 0.388 | 0.3152 | 5.79.E-04 | 0.390 | 0.119 |
BP, biological process; MAF, minor allele frequency; SNP, single-nucleotide polymorphism.