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. 2015 Mar 1;9(3):FC05–FC09. doi: 10.7860/JCDR/2015/11884.5677

[Table/Fig-4]:

Comparison of efficacy and tolerability measures between and within the treatment groups.

Darifenacin p-value Trospium p-value (comparison within the group) p-value (comparison between 2 groups)
Baseline 2 weeks 4 weeks Baseline 2 weeks 4 weeks
Mean ± SD Mean ± SD Mean ± SD Mean ± SD Mean ± SD Mean ± SD
OABSS 9.87 ± 3.75 4.07 ± 3.21 4.07 ± 3.29 0.0005* 1.000 0.0005 9.27 ± 3.21 4.27 ± 3.70 4.00 ± 3.86 0.0005* 0.063 0.0005 2 weeks 0.952
4 weeks 0.654
Bristol stool consistency 2.60 ± 0.97 2.87 ± 0.82 2.47 ± 0.97 0.021* 0.032 0.566 3.07 ± 0.87 3.20 ± 1.24 3.20 ± 1.24 0.076§ 2 weeks 0.227
4 weeks 0.017
KESS questionnaire 3.73 ± 3.45 3.87 ± 4.65 5.27 ± 5.98 0.084§ 3.33 ± 4.41 4.20 ± 4.44 4.00 ± 4.56 0.053* 0.157 0.105 2 weeks 0.858
4 weeks 0.244
McMillan & Williams CAS 0.27 ± 0.58 0.80 ± 1.63 1.20 ± 2.01 0.032* 0.063 0.007 0.53 ± 1.17 1.13 ± 1.89 1.13 ± 1.89 0.011* 1.000 0.011 2 weeks 0.778
4 weeks 0.944

*For comparison between baseline and 2 weeks (Wilcoxon signed ranks test)

For comparison between 2weeks and 4 weeks (Wilcoxon signed ranks test)

For comparison between baseline and 4 weeks (Wilcoxon signed ranks test)

§For overall comparison between baseline, 2 weeks and 4 weeks (Friedman test)

Mann Whitney U-test