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. 2015 Apr 13;13(4):2105–2123. doi: 10.3390/md13042105

Figure 5.

Figure 5

Expression changes in mitochondria pro-apoptotic proteins post burn with ATX administration. Although the expression of Bcl-xL decreased significantly post burn, all doses of ATX did not increase declined Bcl-xL levels (A,B). With regard to cytochrome c and cleaved caspase-3/9, burn insults caused obvious elevations in their protein expression in both burn and vehicle groups (A,C–E). ATX administration remarkably reduced the changes of protein expression, and the 20 mg/kg dose was the most effective (A,C–E). The sample size was n = 6 for each group. The results are expressed as the mean ± SD. ** p < 0.01, vs. sham; ## p < 0.01, vs. burn + vehicle; ns p > 0.05.