Table 1.

Antimicrobial activity of TP3 and TP4 against clinical isolates of A. baumannii, E. coli, or K. pneumonia, as compared with that of piscidin-1 and commonly used antimicrobial agents. (a) Minimum inhibitory concentrations (MIC). (b) Minimum bactericidal concentrations (MBC). ND: not determined.

(a)
Bacterial Strain	TP3	TP4	Piscidin-1	Ampicillin	Imipenem
	(μg/mL)	(μg/mL)	(μg/mL)	(μg/mL)	(μg/mL)
K. pneumoniae (YT32)	3.125	3.125	50	ND	<1.56
E. coli (YT39)	<1.56	<1.56	25	ND	<1.56
E. coli (YT154)	<1.56	<1.56	3.125	ND	<1.56
A. baumannii (Icu53)	<1.56	<1.56	6.25	ND	<1.56
A. baumannii (Sk44)	12.5	<1.56	3.125	ND	50
K. pneumoniae (NDM-1)	25	3.125	50	ND	3.125
K. pneumoniae (blaNDM-1)	3.125	ND	50	ND	<1.56
(b)
Bacterial Strain	TP3	TP4	Piscidin-1	Ampicillin	Imipenem
	(μg/mL)	(μg/mL)	(μg/mL)	(μg/mL)	(μg/mL)
K. pneumoniae (YT32)	3.125	3.125	50	ND	1.56
E. coli (YT39)	1.56	1.56	25	ND	1.56
E. coli (YT154)	1.56	1.56	3.125	ND	1.56
A. baumannii (Icu53)	1.56	1.56	6.25	ND	12
A. baumannii (Sk44)	25	1.56	25	ND	50
K. pneumoniae (NDM-1)	25	3.125	50	ND	6
K. pneumoniae (blaNDM-1)	3.125	ND	50	ND	6