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. 2015 Apr 6;112(16):E2093–E2101. doi: 10.1073/pnas.1504394112

Fig. 4.

Fig. 4.

Spatial distribution of cortical association modules. (A) Modules (M1–M4) in Figs. 2 and 3 plotted on a flatmap of right half of rat central nervous system (16); M1, red; M2, blue, M3, green, M4, yellow. See ref. 16 for high-resolution details. (B) The cortical association connectome (Fig. 1) shown in the context of the complete rat central nervous system connectome that has just 15% matrix coverage (fill ratio) because most literature outside the cortical association domain is not yet expertly curated (44). Abbreviations are in Fig. S2. (C) Histologically defined human cortical regions corresponding to rat cortical regions (correspondence documented in Fig. S2) plotted on a flatmap (45) and color coded as in A. AH, Ammon’s horn; AON, anterior olfactory nucleus; BLC, basolateral amygdalar complex; CLA/6B, claustrum/layer 6b; COC, cortical amygdalar complex; DG, dentate gyrus; EP, entopeduncular nucleus; INS, insular region; OB, olfactory bulb; TT, tenia tecta; SBC, subicular complex. Numbers correspond to Brodmann’s areas (Fig. S2). (D) Predicted fate map of major cerebral cortical regions with general location of rat M1–M4 (color coded as in A and C); illustrated on the right embryonic forebrain vesicle viewed from medial aspect (4-wk human; equivalent to 11-d rat, 9/10-d mouse); adapted from ref. 46. E, epithalamus; H, hypothalamus; N, cerebral nuclei; T, dorsal thalamus; V, ventral thalamus.