Table 2.

[F-18]FDDNP DVR group mean values for mTBI group (14 subjects), control group (28 subjects), and Alzheimer’s disease group (24 subjects)

	Limbic		Subcortical						Cortical
	Amygd	MTL	Midb-V	Midb-D	Hypo-Th	Th	Pons	Str	F	ACG	P	PCG	LTL	OCC
mTBI	1.397 (0.095)	1.183 (0.042)	1.330 (0.090)	1.373 (0.060)	1.429 (0.082)	1.507 (0.107)	1.319 (0.071)	1.531 (0.104)	1.144 (0.049)	1.230 (0.068)	1.095 (0.047)	1.160 (0.077)	1.122 (0.048)	0.997 (0.050)
CTRL	1.162 (0.036)	1.112 (0.023)	1.135 (0.057)	1.138 (0.055)	1.234 (0.049)	1.250 (0.086)	1.156 (0.064)	1.322 (0.069)	1.039 (0.033)	1.093 (0.043)	1.054 (0.026)	1.082 (0.040)	1.064 (0.026)	1.021 (0.048)
AD	1.242 (0.060)	1.189 (0.020)	1.137 (0.062)	1.164 (0.078)	1.229 (0.058)	1.318 (0.109)	1.145 (0.075)	1.345 (0.090)	1.112 (0.027)	1.141 (0.073)	1.148 (0.030)	1.180 (0.022)	1.155 (0.024)	1.059 (0.056)
ANOVA
F value	59.82*	73.26*	29.26*	26.56*	24.36*	15.01*	13.97*	21.82*	45.83*	13.72*	72.00*	44.93*	82.04*	5.43
Student t test
mTBI-CTRL	*	*	*	*	*	*	*	*	*	*	*	*	*	*
mTBI-AD	*	NS	*	*	*	*	*	*	NS	NS	NS	NS	NS	NS
AD-CTRL	*	*	NS	NS	NS	NS	NS	NS	*	NS	*	*	*	NS
Tukey–Kramer test
mTBI-CTRL	*	*	*	*	*	*	*	*	*	*	NS	NS	NS	NS
mTBI-AD	*	NS	*	*	*	NS	*	*	NS	NS	NS	NS	NS	NS
AD-CTRL	*	*	NS	NS	NS	NS	NS	NS	*	NS	*	*	*	NS

Mean group DVR values (SD values given in parentheses). ACG, anterior cingulate gyrus; Amygd, amygdala; F, frontal; Hypo-Th, hypothalamus; LTL, lateral temporal lobe; Midb-D, dorsal midbrain; Midb-V, ventral midbrain; MTL, medial temporal lobe; NS, not significant (P ≥ 0.0001); Occ, occipital; P, parietal; PCG, posterior cingulate gyrus; Str, striatum (caudate nucleus and putamen); Th, thalamus (medial thalamus). *P < 0.0001; NS, not significant (P ≥ 0.0001).