Table 3.
Genotype frequencies of eNOS rs743506, rs207468799, rs2070744 and rs1799983, rs148554851, rs180079, rs3918226, rs207468799 and rs148554851 ene polymorphisms in migraine with and without aura patients and control group.
| eNOS SNPs | Genotype | Without Aura n (%) | With Aura n (%) | Controls n (%) | p Value |
|---|---|---|---|---|---|
| rs743506 | AA | 67 (39.9) | 37 (22.0) | 64 (38.1) | 0.225a |
| AG | 43 (39.1) | 18 (16.4) | 49 (44.5) | ||
| GG | 3 (13.6) | 7 (31.8) | 12 (54.5) | ||
|
| |||||
| rs207468799 | GG | 117 (39.0) | 58 (19.3) | 125 (41.7) | NS |
| GA | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| AA | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
|
| |||||
| rs2070744 | CC | 11 (36.7) | 7 (23.3) | 12 (40.0) | 0.858a |
| CT | 60 (39.2) | 26 (17.0) | 67 (43.89) | ||
| TT | 46 (39.3) | 25 (21.4) | 46 (39.3) | ||
|
| |||||
| rs1799983 | GG | 66 (39.2) | 33 (20.9) | 59 (37.3) | 0.398a |
| GT | 46 (37.1) | 20 (16.1) | 58 (46.8) | ||
| TT | 5 (27.8) | 5 (27.8) | 8 (44.8) | ||
|
| |||||
| rs148554851 | GG | 117 (39.0) | 58 (19.3) | 125 (41.7) | NS |
| GA | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| AA | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
|
| |||||
| rs180079 | GG | 10 (35.7) | 6 (21.4) | 12 (42.9) | 0.963a |
| GA | 61 (39.1) | 28 (17.9) | 67 (42.9) | ||
| AA | 46 (39.7) | 24 (20.7) | 46 (39.7) | ||
|
| |||||
| rs3918226 | GG | 99 (38.2) | 52 (20.1) | 108 (41.7 | 1.000b |
| GA | 18 (45.0) | 5 (12.5) | 17 (42.5) | ||
| AA | 0 (0.0) | 1 (100.0) | 0 (0.0) | ||
eNOS SNPs: endothelial nitric oxide synthase single nt polymorphisms; NS: no statistics were computed.
a
Pearson’s c2 test.
b
Kolmogorov-Smirnov two-sample test.