Table 3. Summary risk estimates for association between SNP rs2511989 and AMD.

Stratifications	Studies (n)	Model	Pooled estimate		Heterogeneity		Egger's test P
			OR (95%CI)	PZ	I2 (%)	PQ
Overall
A vs G	16	R	0.938 (0.858-1.025)	0.155	63.6	<0.001	0.854
AA vs GG	16	R	0.871 (0.719-1.056)	0.159	61.6	0.001	0.948
AG vs GG	16	R	0.944 (0.845-1.054)	0.306	50.1	0.012	0.280
AA+AG vs GG	16	R	0.927 (0.823-1.044)	0.211	61.2	0.001	0.387
AA vs AG+GG	16	R	0.890 (0.780-1.034)	0.135	41.9	0.040	0.595
Asians
A vs G	3	F	1.002 (0.857-1.171)	0.984	0.0	0.725	0.615
AA vs GG	3	F	1.042 (0.604-1.800)	0.882	30.6	0.237	0.407
AG vs GG	3	F	0.993 (0.830-1.187)	0.935	0.0	0.993	0.352
AA+AG vs GG	3	F	0.998 (0.839-1.187)	0.980	0.0	0.948	0.435
AA vs AG+GG	3	F	1.043 (0.605-1.797)	0.880	31.6	0.232	0.614
Caucasians
A vs G	13	R	0.925 (0.835-1.024)	0.134	70.0	<0.001	0.603
AA vs GG	13	R	0.853 (0.697-1.045)	0.124	66.4	<0.001	0.621
AG vs GG	13	R	0.930 (0.811-1.067)	0.300	59.8	0.003	0.310
AA+AG vs GG	13	R	0.908 (0.785-1.051)	0.195	68.4	<0.001	0.360
AA vs AG+GG	13	R	0.889 (0.769-1.028)	0.112	46.7	0.032	0.956
Age-matched
A vs G	10	F	1.018 (0.957-1.083)	0.571	0.0	0.562	0.802
AA vs GG	10	F	1.029 (0.904-1.172)	0.662	0.0	0.713	0.388
AG vs GG	10	F	1.049 (0.956-1.152)	0.314	25.1	0.212	0.504
AA+AG vs GG	10	F	1.043 (0.955-1.140)	0.345	17.5	0.282	0.667
AA vs AG+GG	10	F	0.989 (0.879-1.113)	0.858	0.0	0.797	0.079
Age-unmatched
A vs G	6	R	0.813 (0.695-0.951)	0.010	66.2	0.011	0.285
AA vs GG	6	R	0.619 (0.434-0.883)	0.008	60.8	0.026	0.405
AG vs GG	6	F	0.812 (0.715-0.921)	0.001	36.3	0.165	0.503
AA+AG vs GG	6	R	0.771 (0.634-0.939)	0.010	61.3	0.024	0.620
AA vs AG+GG	6	R	0.716 (0.528-0.973)	0.033	55.4	0.047	0.628

R: Random-effects model; F: Fixed-effects mode; P_Z: P value for Z test; P_Q: P value for Q test.