Table 2. List of the top GO terms in the most significant DAVID functional clusters for each network module.
Module | Top terms | No. of genes in ME | P | FDR |
Blue | GO:0006414: translational elongation | 1030 | 1.48e-48 | 2.54E-95 |
GO:0006412: translation | 2.88e-97 | 4.94e-49 | ||
GO:0006091: generation of precursor metabolites and energy | 1.59e-37 | 2.72e-34 | ||
GO:0006119: oxidative phosphorylation | 3.51e-36 | 6.02e-33 | ||
GO:0022900: electron transport chain | 4.51e-36 | 7.73e-26 | ||
Purple | GO:0030036: actin cytoskeleton organization | 49 | 0.001889 | 2.673499 |
GO:0030029: actin filament-based process | 0.002387 | 3.366931 | ||
GO:0007010: cytoskeleton organization | 0.003335 | 4.674312 | ||
GO:0006936: muscle contraction | 0.005533 | 7.642884 | ||
GO:0055002: striated muscle cell development | 0.006677 | 9.154233 | ||
Red | GO:0009611: response to wounding | 290 | 1.96E-20 | 3.32E-17 |
GO:0006954: inflammatory response | 7.91E-17 | 1.89E-13 | ||
GO:0006952: defense response | 1.90E-16 | 3.77E-13 | ||
GO:0002504: antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | 8.16E-13 | 1.38E-09 | ||
GO:0006955: immune response | 1.40E-12 | 2.37E-09 | ||
Black | GO:0006355:regulation of transcription, DNA-dependent | 119 | 1.10E-04 | 0.172753 |
GO:0010629:negative regulation of gene expression | 1.40E-04 | 0.220258 | ||
GO:0051252:regulation of RNA metabolic process | 1.54E-04 | 0.242911 | ||
GO:0016481:negative regulation of transcription | 2.92E-04 | 0.459812 | ||
GO:0045449:regulation of transcription | 4.00E-04 | 0.629367 |
FDR: False discovery rate; ME: Module eigengene.