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. 2014 Dec 17;6(5):2709–2724. doi: 10.18632/oncotarget.2779

Table 1. Pathway analysis of genes co-expressed with PDGFRα, PDGFRβ, and c-MYC in MB tumors.

PDGFRα PDGFRβ c-MYC
Antigen_processing_and_presentation graphic file with name oncotarget-06-2709-i008.jpg Adherens_junction graphic file with name oncotarget-06-2709-i007.jpg Ubiquitin_mediated_proteolysis graphic file with name oncotarget-06-2709-i007.jpg
Arachidonic_acid_metabolism graphic file with name oncotarget-06-2709-i007.jpg Amoebiasis* graphic file with name oncotarget-06-2709-i010.jpg Spliceosome graphic file with name oncotarget-06-2709-i007.jpg
Basal_cell_carcinoma graphic file with name oncotarget-06-2709-i009.jpg Antigen_processing_and_presentation graphic file with name oncotarget-06-2709-i009.jpg Ribosome_biogenesis_in_eukaryotes graphic file with name oncotarget-06-2709-i008.jpg
ECM_receptor_interaction graphic file with name oncotarget-06-2709-i010.jpg Apoptosis* graphic file with name oncotarget-06-2709-i007.jpg Ribosome graphic file with name oncotarget-06-2709-i008.jpg
Focal_adhesion graphic file with name oncotarget-06-2709-i009.jpg Cell_adhesion_molecules__CAMs* graphic file with name oncotarget-06-2709-i010.jpg Protein_processing_in_endoplasmic_reticulum* graphic file with name oncotarget-06-2709-i009.jpg
Hedgehog_signaling_pathway* graphic file with name oncotarget-06-2709-i007.jpg Complement_and_coagulation_cascades graphic file with name oncotarget-06-2709-i010.jpg Protein_export* graphic file with name oncotarget-06-2709-i009.jpg
Hippo_signaling_pathway graphic file with name oncotarget-06-2709-i009.jpg Cytokine_cytokine_receptor_interaction* graphic file with name oncotarget-06-2709-i008.jpg Olfactory_transduction* graphic file with name oncotarget-06-2709-i007.jpg
Insulin_secretion graphic file with name oncotarget-06-2709-i007.jpg ECM_receptor_interaction graphic file with name oncotarget-06-2709-i010.jpg Neuroactive_ligand_receptor_interaction graphic file with name oncotarget-06-2709-i007.jpg
Leukocyte_transendothelial_migration graphic file with name oncotarget-06-2709-i009.jpg Focal_adhesion graphic file with name oncotarget-06-2709-i010.jpg N_Glycan_biosynthesis* graphic file with name oncotarget-06-2709-i009.jpg
Lysosome graphic file with name oncotarget-06-2709-i007.jpg Hematopoietic_cell_lineage* graphic file with name oncotarget-06-2709-i009.jpg Measles* graphic file with name oncotarget-06-2709-i007.jpg
Neuroactive_ligand_receptor_interaction* graphic file with name oncotarget-06-2709-i007.jpg Inflammatory_bowel_disease__IBD_ graphic file with name oncotarget-06-2709-i007.jpg Jak_STAT_signaling_pathway* graphic file with name oncotarget-06-2709-i007.jpg
Pathways_in_cancer graphic file with name oncotarget-06-2709-i008.jpg Insulin_secretion graphic file with name oncotarget-06-2709-i007.jpg Glycolysis_Gluconeogenesis* graphic file with name oncotarget-06-2709-i007.jpg
Phagosome graphic file with name oncotarget-06-2709-i007.jpg Leukocyte_transendothelial_migration graphic file with name oncotarget-06-2709-i010.jpg Cytokine_cytokine_receptor_interaction graphic file with name oncotarget-06-2709-i007.jpg
PI3K_Akt_signaling_pathway graphic file with name oncotarget-06-2709-i010.jpg MicroRNAs_in_cancer* graphic file with name oncotarget-06-2709-i007.jpg
Protein_digestion_and_absorption graphic file with name oncotarget-06-2709-i009.jpg NF_kappa_B_signaling_pathway* graphic file with name oncotarget-06-2709-i007.jpg
Proteoglycans_in_cancer graphic file with name oncotarget-06-2709-i007.jpg Pathways_in_cancer graphic file with name oncotarget-06-2709-i010.jpg
Regulation_of_actin_cytoskeleton graphic file with name oncotarget-06-2709-i009.jpg Phagosome graphic file with name oncotarget-06-2709-i009.jpg
Ribosome* graphic file with name oncotarget-06-2709-i009.jpg PI3K_Akt_signaling_pathway graphic file with name oncotarget-06-2709-i010.jpg
Staphylococcus_aureus_infection graphic file with name oncotarget-06-2709-i009.jpg Protein_digestion_and_absorption graphic file with name oncotarget-06-2709-i010.jpg
Sulfur_metabolism* graphic file with name oncotarget-06-2709-i008.jpg Proteoglycans_in_cancer graphic file with name oncotarget-06-2709-i009.jpg
Wnt_signaling_pathway* graphic file with name oncotarget-06-2709-i008.jpg Regulation_of_actin_cytoskeleton graphic file with name oncotarget-06-2709-i008.jpg
Small_cell_lung_cancer* graphic file with name oncotarget-06-2709-i009.jpg
Staphylococcus_aureus_infection graphic file with name oncotarget-06-2709-i010.jpg
TNF_signaling_pathway* graphic file with name oncotarget-06-2709-i008.jpg
Viral_myocarditis graphic file with name oncotarget-06-2709-i009.jpg

The major pathways identified from human MBs based on the highly co-expressed genes.

*

Genes in the pathways are specifically co-expressed with PDGFRα, or PDGFRβ, or c-MYC in MBs

The frequency of pathways found in 5 sets of data are marked as following: 2 out of 5: Inline graphic 3 out of 5: Inline graphic 4 out of 5: Inline graphic 5 out of 5: Inline graphic