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. 2014 Dec 30;6(5):2827–2842. doi: 10.18632/oncotarget.3090

Figure 1. Schematic representations of DOX nanoparticles, targeted DOX nanoparticles and functional DOX nanoparticles.

Figure 1

(A) and the mechanism of functional DOX nanoparticles' effect on cells with MDR (B, C). The functional DOX nanoparticles, which consisted of FPRs, DQA, and DOX, overcame DOX resistance in vitro by targeting the mitochondria of MCF-7/Adr cells.