Table 2. MIR196B target genes.
| Gene symbol | Accession | Gene name | Chromosome location | Functions |
|---|---|---|---|---|
| HOXB7 | NM_004502.3 | homeobox B7 | 17q21.3 | transcription factor |
| HOXC8 | NM_022658.3 | homeobox C8 | 12q13.3 | transcription factor |
| HOXA9 | NM_152739.3 | homeobox A9 | 7p15.2 | transcription factor |
| GLTP | NM_016433.3 | glycolipid transfer protein | 12q24.11 | transfer/carrier protein |
| LAMTOR5 | NM_006402.2 | late endosomal adaptor, MAPK and MTOR activator 5 | 1p13.3 | regulate HBx activity |
| ANXA1 | NM_000700.1 | annexin A1 | 9q21.13 | transfer/carrier protein |
| APEX2 | NM_014481.2 | APEX nuclease 2 | Xp11.21 | nucleic acid binding |
| FAS | NM_152877.1 | cell surface death receptor | 10q24.1 | signal transduction |
| HAND1 | NM_004821.1 | heart and neural crest derivatives expressed 1 | 5q33 | transcription factor |
| HOXA5 | NM_019102.2 | homeobox A5 | 7p15.2 | transcription factor |
| HOXB6 | NM_018952.4 | homeobox B6 | 17q21.3 | transcription factor |
| KCNIP3 | NM_013434.4 | Kv channel interacting protein 3, calsenilin | 2q21.1 | calcium binding protein |
| LRRC49 | NM_017691.2 | leucine rich repeat containing 49 | 15q23 | - |
| MED10 | NM_032286.2 | mediator complex subunit 10 | 5p15.31 | transcription factor |
| MRPL39 | NM_017446.3 | mitochondrial ribosomal protein L39 | 21q21.3 | synthase and synthetase |
| SPRED1 | NM_152594.1 | sprouty-related, EVH1 domain containing 1 | 15q14 | receptor |
| TGFB1I1 | NM_015927.3 | transforming growth factor beta 1 induced transcript 1 | 16p11.2 | transcription cofactor |
| VSNL1 | NM_003385.4 | visinin-like 1 | 2p24.3 | calcium binding protein |
The target genes were identified by comparing mRNAs down-regulated in MIR196B-overexpressing cells with target genes predicted by public bioinformatics tools (TargetScan (http://www.targetscan.org) and miRWalk (http://www.umm.uni-heidelberg.de/apps/zmf/mirwalk/index.html).