Figure 1. Crosstalk among ERK, AKT and Hippo-YAP pathways.
(A) Effects of PI3K inhibitor, LY294002, AKT inhibitor, MK-2206, and ERK inhibitor, PD0325901, on AKT, ERK and Hippo-YAP pathways. (B) Effects of ERK silencing on AKT, ERK and Hippo-YAP pathway. (C) Quantification of p-AKT, p-ERK and p-YAP upon treatment with LY294002, MK-2206 and PD0325901. (D) Quantification of p-AKT, p-ERK and p-YAP upon ERK silencing.