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. 2014 Dec 30;6(5):2951–2965. doi: 10.18632/oncotarget.3095

Figure 7. A paradigm showing the signaling network crosstalk among ERK, AKT and Hippo-YAP pathways, where CD44 functions as a common upstream regulator sensing cellular contact inhibition.

Figure 7

Positive regulation is shown as an arrow. Negative regulation is depicted as a blunt-ended line.