Figure 2. Effect of NRs on PCa cell growth and colony formation.

(A) Representative photographs of colonies formed in PCa cells at 14^th day after initial treatment with specified compounds (5 μmol/L). Colonies were fixed with methanol and stained with crystal violet. (B) Data represents the mean ± S.E from three independent experiments. *, P< 0.05; ♣, P<0.01 compared to vehicle treated control. (C) Effect of NRs on growth of Enzalutamide resistant MR49F cells. NRs that had promising inhibitory effect on cell proliferation on LNCaP cells were tested for their growth inhibitory effect in MR49F cells in comparison with Casodex and Abiraterone acetate by MTT assay.