Skip to main content
. 2014 Sep 9;26(5):1195–1204. doi: 10.1681/ASN.2014010096

Figure 2.

Figure 2.

Minor allele A of rs6677604 highly tagged CFHR3–1 deletion (CFHR3–1∆). Pie charts show the proportion of different copy numbers of CFHR3 and CFHR1 in patients with IgAN and healthy controls with rs6677604-AA, -AG, and -GG genotypes. In our population, 100% of individuals (41 of 41 patients with IgAN and 28 of 28 healthy controls) with rs6677604-GG had two copies of CFHR3 and CFHR1. All individuals (42 of 42 patients with IgAN and 55 of 55 healthy controls) with rs6677604-AG had one copy of CFHR3, whereas all individuals (5 of 5 healthy controls) with rs6677604-AA had no copies of CFHR3. In patients with IgAN with rs6677604-AG, 93% (39 of 42) had one copy of CFHR1, and the remaining 7% (3 of 42) had two copies of CFHR1. In healthy controls with rs6677604-AG, 89% (49 of 55) had one copy of CFHR1, 7% (4 of 55) had two copies of CFHR1, and 4% (2 of 55) had no copies of CFHR1. Of five controls with rs6677604-AA, four (80%) had no copies of CFHR1, and one (20%) had one copy of CFHR1.