Table 2.
Summary of comparisons.
| Library size | Input subtraction | |||||
|---|---|---|---|---|---|---|
| Effective | Full | TMM | MAnorm | None | scale CPM | |
| edgeR default | x | x | x | |||
| edgeR full | x | x | ||||
| DiffBind default | x | x | x | |||
| DiffBind full | x | x | x | |||
| MAnorm3 | x* | x | x | |||
| Voom | x | x | ||||
Each type of analysis is shown with a different row with X indicating the option(s) that was chosen.
MAnorm3 takes the average of log transformed effective library sizes for scaling.