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. 2015 Mar 13;176(15):384. doi: 10.1136/vr.102892

TABLE 4:

Summary of Leptospirosis test results for the 5 dogs with positive Leptospira serology

Case Serovar for which positive result was obtained Titre Time (in months) since administration of last leptospirosis vaccine (canicola, icterohaemorrhagiae) Timing of serology postdevelopment of skin lesions (days) Timing of serology postdevelopment of systemic signs (days) PCR on urine PCR on blood PCR on renal tissue*† FISH result* Previous anti-biotics?
1 L. bratislava
L. australis
1:400
1:100
7 6 2 Negative Negative Not performed Positive on renal tissue, diffuse No
2 L. copenhageni
L. canicola
L. icterohaemorrhagiae
1:800
1:100
1:200
10 5 1 Not performed Not performed Not performed Positive on renal tissue, diffuse Yes
3 L. canicola
L. copenhageni
1:100
1:100
8 6 2 Not performed Not performed Positive*
Negative†
Positive on renal tissue, clusters Yes
4 L. autumnalis
L. icterohaemorrhagiae
L. copenhageni
L. bratislava
1:400
1:100
1:100
1:100
7 2 2 Negative Not performed Negative†

Nega tive on liver tissue also*
Not performed on renal tissue
Negative on liver tissue
Yes
5 Not specified +ve combined IgG 2 5 Same day Not performed Not performed Positive* Positive, clusters Yes

*University of Bristol Veterinary Diagnostics

†Idexx Laboratories

FISH, fluorescence in situ hybridisation