Table 2.
Non-depressed controlsa (<16 on CES-D & no antidepressants) | Remitted depressionb (<16 on CES-D & on antidepressants) | Current depressionc (⩾16 on CES-D & no antidepressants) | Current depressiond (⩾16 on CES-D & on antidepressants) | Controls v. | ||||||
---|---|---|---|---|---|---|---|---|---|---|
(N = 4107) | (N = 185) | (N = 317) | (N = 80) | Remitted (<16 on CES-D and on antidepressants) | Current depression (no antidepressants) | Current depression (on antidepressants) | ||||
Mean (s.e.) | Mean (s.e.) | Mean (s.e.) | Mean (s.e.) | Effect sizeb | p value | Effect sizeb | p value | Effect sizeb | p value | |
HR (beats/min) | ||||||||||
Unadjusted | 66.2 (0.17) | 69.4 (0.98) | 66.7 (0.61) | 69.3 (1.4) | −3.2 | 0.00** | −0.79 | 0.42 | −2.4 | 0.01** |
Adjusteda | 66.3 (0.03) | 66.7 (0.16) | 67.1 (0.13) | 67.3 (0.26) | 2.0 | 0.04* | 3.9 | 0.00** | 2.7 | 0.01** |
SDNNc | ||||||||||
Unadjusted | 40.7 (1.0) | 32.3 (1.0) | 38.9 (1.0) | 34.6 (1.1) | 4.5 | 0.00** | 2.2 | 0.06 | 2.2 | 02* |
Adjusteda | 40.7 (1.0) | 38.9 (1.0) | 39.8 (1.0) | 39.7 (1.0) | −6.11 | 0.00** | −1.1 | 0.25 | −2.0 | 0.04* |
LFd (ms2) | ||||||||||
Unadjusted | 151.3 (1.0) | 83.1 (1.1) | 128.8 (1.1) | 102.3 (1.1) | 5.0 | 0.00** | 1.7 | 0.02* | 3.4 | 0.00** |
Adjusteda | 147.9 (1.0) | 128.8 (1.0) | 144.5 (1.0) | 134.8 (1.1) | −8.5 | 0.00** | −1.3 | 0.18 | −2.5 | 0.01** |
HFe (ms2) | ||||||||||
Unadjusted | 158.4 (1.0) | 97.7 (1.1) | 147.9 (1.1) | 97.7 (1.2) | 2.4 | 00** | 1.0 | 0.41 | 2.4 | 0.01** |
Adjusteda | 158.8 (1.0) | 147.2 (1.0) | 155.0 (1.0) | 144.8 (1.1) | −4.8 | 0.00** | 1.0 | 0.31 | 2.3 | 0.02* |
HR, Heart rate; SDNN, standard deviation of normal to normal intervals (SDNN); LF, low frequency; HF, high frequency; CES-D, Center for Epidemiologic Studies – Depression scale.
Adjusted for age, sex, education, body mass index, physical activity, smoking, alcohol use, heart disease, chronic disease, heart medication, anxiety.
t test used for unadjusted means, z test used for adjusted means.
Denotes significance at 0.05.
Denotes significance at 0.01.