Figure 2.

Comparison of different visualizations and indices of a static perimetry exam from a 63-year-old patient with mild autosomal dominant retinitis pigmentosa from the frameshift mutation, NM_006,269.1:c.3157delT(P.Tyr1053ThrfsX4) of RP1⁸ in association with a second, novel heterozygous mutation in RP9, NM_203,288.1:c664delT, which is predicted to eliminate a stop codon and add 28 amino acids to the RP9 protein. (a) Scaled-point plot in which each grid location is scaled in size to reflect the DLS value. (b) Incremental color-scale plot generated by the Octopus 900 (Haag-Streit). (c) Oblique view of the 3-D hill of vision model generated by VFMA, with iso-sensitivity contours at 2 dB intervals. (d) Oblique view of the 3-D defect space model generated by VFMA showing peripheral field loss. (e) En face view with the selection boundaries for the total volume (blue/black) and the central 30° volume (white/black). (f) En face view of the defect space created by subtraction of the patient DLS values from those of an age-matched normal. The D_TOT and D_30° indices for this eye indicate substantial loss of peripheral field with minimal loss of central field. The blind spot and its inverted peak can be seen in (c), (d), and (e); the blind spot was removed in (f) to mitigate its effects on the defect space volumetric measurements.