Table 3.
KEGG pathway classification of gene expression in T cell mediated colitis
| KEGG Pathway | List | Gene Set | z-score |
|---|---|---|---|
| Metabolic pathways | 63 | 1061 | −4.31 |
| Cytokine-cytokine receptor interaction | 54 | 232 | 7.49 |
| Chemokine signaling pathway | 42 | 173 | 6.89 |
| Cell adhesion molecules (CAMs) | 34 | 131 | 6.64 |
| Natural killer cell mediated cytotoxicity | 33 | 124 | 6.71 |
| Endocytosis | 30 | 201 | 2.79 |
| Systemic lupus erythematosus | 28 | 81 | 7.88 |
| Antigen processing and presentation | 24 | 71 | 7.15 |
| Chagas disease | 23 | 102 | 4.64 |
| Leishmaniasis | 22 | 66 | 6.75 |
| Viral myocarditis | 22 | 72 | 6.24 |
| Graft-versus-host disease | 21 | 38 | 9.78 |
| Jak-STAT signaling pathway | 20 | 138 | 2.12 |
| T cell receptor signaling pathway | 20 | 107 | 3.37 |
| Type I diabetes mellitus | 20 | 44 | 8.28 |
| Allograft rejection | 19 | 38 | 8.66 |
| Leukocyte transendothelial migration | 19 | 114 | 2.73 |
| Vascular smooth muscle contraction | 19 | 122 | 2.4 |
| Autoimmune thyroid disease | 18 | 49 | 6.63 |
| Neuroactive ligand-receptor interaction | 17 | 285 | −2.01 |
| Fc gamma R-mediated phagocytosis | 16 | 87 | 2.93 |
| Hematopoietic cell lineage | 16 | 79 | 3.37 |
| B cell receptor signaling pathway | 14 | 76 | 2.75 |
| Intestinal immune network for IgA production | 14 | 43 | 5.26 |
| Malaria | 13 | 47 | 4.34 |
| NOD-like receptor signaling pathway | 12 | 55 | 3.2 |
| Asthma | 9 | 25 | 4.6 |
| Primary immunodeficiency | 9 | 34 | 3.45 |
| Prion diseases | 9 | 34 | 3.45 |
| Alzheimer's disease | 7 | 154 | −2.07 |
| Circadian rhythm - mammal | 5 | 13 | 3.62 |
| Huntington's disease | 5 | 160 | −2.74 |
| Ubiquitin mediated proteolysis | 5 | 134 | −2.26 |