Table 2.

Changes in plasma soluble adhesion molecule, matrix metalloproteinase concentrations and LDL oxidisability during a glucose tolerance test in 21 patients with Type 2 diabetes and 20 controls.

	Time [mins]
	0	60	90	120	p
Type 2 diabetes
Blood glucose [mmol/l]	8.6 [2.7]	16.1 [3.8] *	17.8 [3.5] *	17.0 [3.6] *	0.0001
s ICAM-1 [ng/ml]	276 [85]	249 [76] *	249 [79] *	247 [78] *	0.0001
s VCAM-1 [ng/ml]	528 [222]	486 [216] *	472 [208] *	459 [194] *	0.0001
s E-Selectin [ng/ml]	82 [33]	76 [31]*	74 [32] *	75 [32] *	0.0001
LDL lag time [mins]	54. 8 [9.8]	-	52.2 [9.3]		ns
Plasma triglycerides [mmol/l]	2.5 [0.9]	-	2.4 [0.7]		ns
MMP-3 [ng/ml]	13.7 [0 – 71]	-	18.0 [0 – 85]		ns
MMP-9 [ng/ml]	0.0 [0 – 129]	-	0.0 [0 – 75]		ns
Controls
Time [mins]	0	60	90	120	p
Blood glucose [mmol/l]	4.6 [0.3]	7.0 [1.2] *	6.0 [1.1] *	5.4 [1.1] *	0.0001
s ICAM-1 [ng/ml]	280 [82]	219 [57] *	257 [70] *	230 [71] *	0.0001
s VCAM-1 [ng/ml]	321 [198]	349 [197]	321 [174]	338.7 [182]	0.23
s E-Selectin [ng/ml]	64 [24]	60 [21]	58 [22] **	59 [21]	0.003
LDL lag time [mins]	71.3 [8.1]		74.3 [10.2]		ns
Plasma triglycerides [mmol/l]	1.6 [0.7]		1.7 [0.8]		ns
MMP-3 [ng/ml]	30.8 [12.8 – 39]		26.4 [4.3 – 37.4]		ns
MMP-9 [ng/ml]	4.7 [1.2 – 41]		11.1 [2.5 – 41.9] *		0.03

Abbreviations as in text. All data shown as mean [SD] or as a median and range [MMP-3 and 9] and p values are for one way repeated measure ANOVA for each variable with * = p < 0.001, ** = p < 0.01 compared to time 0.