Table 3.
Multi-level random effects logistic regression model of individual and area-level factors associated with later stage diagnosis of breast cancer, among white and black women in Maryland, 1992–2003 (32,673 women in 3565 census blockgroups, Maryland cancer registry)
| Model 1 | Model 2 | Model 3 | Model 4 | Model 5 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Fixed Effects | O.R. | 95% CI | O.R. | 95% CI | O.R. | 95% CI | O.R. | 95% CI | O.R. | 95% CI |
| Intercept | 0.32 | (0.31,0.33) | 0.32 | (0.31,0.34) | 0.32 | (0.31,0.33) | 0.33 | (0.29,0.38) | 0.33 | (0.28,0.39) |
| Individual Level | ||||||||||
| Age | 0.99 | (0.97,0.98) | 0.99 | (0.99,0.99) | 0.99 | (0.99,0.99) | 0.99 | (0.99,0.99) | 0.99 | (0.99,0.99) |
| Black Race | 1.24 | (1.17,1.32) | 1.15 | (1.08,1.22) | 1.18 | (1.11,1.26) | 1.18 | (1.10,1.26) | 1.19 | (1.10,1.28) |
| Aggressive Grade | 2.20 | (2.09,2.31) | 2.19 | (2.08,2.30) | 2.19 | (2.08,2.30) | 2.19 | (2.08,2.29) | 2.19 | (2.08,2.29) |
| Year of Diagnosis | 0.98 | (0.97,0.98) | 0.98 | (0.97,0.99) | 0.98 | (0.97, 0.99) | 0.98 | (0.97,0.99) | 0.98 | (0.97,0.99) |
| Census Blockgroup | ||||||||||
| Social Class | 0.89 | (0.86,0.91) | 0.87 | (0.84,0.89) | 0.96 | (0.83,0.90) | 0.86 | (0.83,0.90) | ||
| Class*Black Race | 1.09 | (1.02, 1.16) | 1.09 | (1.03,1.16) | 1.10 | (1.03,1.17) | ||||
| Tobacco Spending (per $100) | 1.00 | (0.98,1.02) | 1.00 | (0.97,1.02) | ||||||
| Tobacco*Black Race | 1.00 | (0.97,1.05) | ||||||||
| Random Effects | Estimate | P Value | Estimate | P Value | Estimate | P Value | Estimate | P Value | Estimate | P Value |
| Blockgroup Level Variance | 0.03343 | <0.0001 | 0.02168 | <0.0001 | 0.02091 | <0.0001 | 0.02089 | <0.0001 | 0.02083 | <0.0001 |
| Residual ICC | 0.01066 | 0.001 | 0.0655 | 0.028 | 0.00632 | 0.032 | 0.00631 | 0.033 | 0.00629 | 0.033 |
Among women with a stage of diagnosis recorded, those whose SEER stage was 2–7, compared to stage 1.
Age in years, centered at the median age of 59. Year of Diagnosis is centered at 1997.
Census blockgroup social class index standardized by subtracting median (272), dividing by the standard deviation (37.7).
Census blockgroup estimated tobacco spending is average per household, in units of $100, and is centered at median (7).
Significance of variance of the blockgroup-level random intercept, calculated with the Wald X 2 test.
Significance of the residual intraclass (within blockgroup) correlation based on the likelihood ratio X 2 test.