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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Mol Microbiol. 2015 Feb 18;96(2):349–367. doi: 10.1111/mmi.12938

Fig. 3. The effect of mutations in NADH-users.

Fig. 3

A. The expanded view of the “electron transport” part of the Fig. 1A scheme. B. Kinetics of CN+HP killing: the fre mutant shows partial resistance, while Fre overproduction elevates CN+HP sensitivity of WT cells. The pFre+ plasmid is pES1. C. Kinetics of killing by the two treatments of ndh and nuo mutants. The nuo mutant behaves like WT, whereas ndh is hyper-sensitive to CN+HP, but shows no sensitivity to HP-alone. D. Comparison of WT chromosome fragmentation kinetic pattern to the ones in the ndh and fre mutants. E. The two treatment survival of the cytochrome oxidase mutants. For clarity, sensitivity is shown at a single time point of 60 minutes (HP-alone) or 45 minutes (CN+HP).