Table 1.

Subjects for serum determination of Fn^EDA. The serum creatinine level was 0.74 ± 0.2mg/dl (mean±SD), and only 3 of 48 patients had serum creatinine level >1.0 mg/dl; none had levels >1.35 mg/dl. Controls were healthy women (median age, 49 years; range, 34 to 62 years). dcSSc diffuse cutaneous SSc DLco, diffusing capacity for carbon monoxide; F, female; FVC, forced vital capacity; lcSSc limited cutaneous SSc; M, male; mRSS, modified Rodnan skin score (1 to 51).

Study code	Age (years)	Sex	Disease subtype	Disease stage (early/late)*	mRSS	FVC (% predicted)	DLco (% predicted)
SScReg_1010_2	57	F	dcSSc	Late	15	99	74
SScReg_1024_2	54	F	dcSSc	Late	22	67	86
SScReg_1073_2	61	F	dcSSc	Late	9	73	60
SScReg_1080_2	55	F	dcSSc	Early	19	81	82
SScReg_1084_2	57	M	dcSSc	Late	10	80	72
SScReg_1100_2	39	F	dcSSc	Early	14	61	43
SScReg_1107_2	48	M	dcSSc	Early	25	96	94
SScReg_1121_2	47	F	dcSSc	Late	26	71	75
SScReg_1046_2	37	F	dcSSc	Late	21	73	62
SScReg_1154_2	56	F	dcSSc	Late	13	87	85
SScReg_1156_2	48	F	dcSSc	Early	23	77
SScReg_1141_2	52	F	dcSSc	Early	16	75	53
SScReg_1182_2	50	F	dcSSc	Late	9	77	61
SScReg_1213_3	30	F	dcSSc	Late	10	81	82
SScReg_1266_3	66	F	dcSSc	Early	14	64	72
SScReg_1068_2	49	F	dcSSc	Late	27	83	88
SScReg_1097_2	64	F	dcSSc	Early	9	66	65
SScReg_1103_2	54	F	dcSSc	Late	13	70	70
SScReg_1043_2	61	F	dcSSc	Late	7	78	72
SScReg_1095_2	42	F	dcSSc	Late	11	83	60
SScReg_1102_3	29	F	dcSSc	Late	20	72	56
SScReg_1048_3	39	M	dcSSc	Late	12	89	81
SScReg_1117_3	45	F	dcSSc	Late	23	94	65
SScReg_1221_3	57	F	dcSSc	Early	12	95	81
SScReg_1248_2	63	F	dcSSc	Late	36	97	64
SScReg_1258_1	57	F	dcSSc	Late	2	90	55
SScReg_1271_2	50	F	dcSSc	Late	25	56	43
SScReg_1279_3	59	F	dcSSc	Late	12	75	60
SScReg_1313_3	62	F	dcSSc	Late	49	86	44
SScReg_1332_2	47	F	dcSSc	Late	26	50	21
SScReg_1354_3	42	F	dcSSc	Early	29	100	76
SScReg_1370_2	45	F	dcSSc	Early	23	100	71
SScReg_1380_2	56	F	dcSSc	Early	7	91	42
SScReg_1386_2	63	F	dcSSc	Early	22	102	53
SScReg_1366_2	55	F	dcSSc	Early	23	76	75
SScReg_1392_3	47	F	dcSSc	Early	19	67	76
SScReg_1397_3	52	F	dcSSc	Late	22	105	64
SScReg_1402_3	48	F	dcSSc	Early	7	72	21
SScReg_1405_3	52	F	dcSSc	Early	13	77	58
SScReg_1410_3	56	F	dcSSc	Early	17	81	77
SScReg_1006_3	47	F	dcSSc	Late	3	101	99
SScReg_1412_3	65	F	dcSSc	Late	6	100	96
SScReg_1119_3	56	M	dcSSc	Late	38	41	26
SScReg_1198_3	59	F	dcSSc	Late	5	76	53
SScReg_1393_3	41	F	dcSSc	Late	14	40	42
SScReg_1320_3	31	F	dcSSc	Late	10	44	60
SScReg_1070_3	62	F	dcSSc	Late	13	25	15
SScReg_1426_2	28	F	dcSSc	Late	18	89	82

^*Early, <2 years from first non-Raynaud disease manifestation; late, >2 years from first non-Raynaud manifestation.