Table 2.
Subjects providing skin biopsies for mRNA analysis. None of the subjects had renal failure. Controls were healthy subjects (median age, 37 years; range, 30 to 63 years); 70% of the patients are female. PM, polymyositis overlap; EMS, eosinophilia-myaglia syndrome.
| Study code | Age (years) | Sex | Disease subtype | Disease stage* | mRSS |
|---|---|---|---|---|---|
| S1001 | 52 | F | dcSSc | Late | 24 |
| SSc01LA | 48 | F | dcSSc | Early | 21 |
| SSc01BLA | 46 | F | dcSSc | Early | 3 |
| SSc02BLA | 41 | F | dcSSc | Early | 21 |
| SSc03LA | 55 | F | lcSSc | Early | 11 |
| SSc04LA | 60 | F | lcSSc | Late | 4 |
| SSc05RA | 66 | F | dcSSc | Early | 9 |
| SSc06BRA | 53 | F | dcSSc | Early | 13 |
| SSc07BLA | 52 | F | dcSSc | Early | 17 |
| SSc08BLA | 34 | F | dcSSc | Late | 32 |
| SSc10BLA | 27 | F | dcSSc | Late | 26 |
| SSc12 BLA | 21 | M | dcSSc | Early | 15 |
| SSc1002BLA | 56 | F | dcSSc | Late | 34 |
| SSc1004BLA | 55 | F | dcSSc | Early | 19 |
| SSc1066LA | 26 | F | lcSSc | Late | 5 |
| SSc1067LA | 54 | F | dcSSc | Late | 13 |
| SSc1080LA | 48 | F | SSc/PM | Early | 20 |
| SSc1096LA | 45 | F | EMS | Early | 23 |
| SSc1103BLA | 30 | F | dcSSc | Late | 4 |
| SSc1156BLA | 50 | F | dcSSc | Early | 14 |
*
Early, <2 years from first non-Raynaud disease manifestation;late, >2 years from first non-Raynaud manifestation.