Skip to main content
. Author manuscript; available in PMC: 2015 Apr 29.
Published in final edited form as: Nat Biotechnol. 2003 Oct 12;21(11):1321–1327. doi: 10.1038/nbt889

Figure 4.

Figure 4

The interaction between VpuC and β-TrCP is important for efficient CXCR4 downregulation. (a) A representative FACS plot of independent SupT1 infections showing CXCR4 surface expression 1 week after transduction. Similar results were observed in Jurkat cells. (b) Total cytoplasmic lysates were analyzed by western blotting with a polyclonal anti-CXCR4. NIH3T3 cells stably expressing human CXCR4 were used as a positive control. Similar results were observed in two independent experiments.