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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: JAMA Ophthalmol. 2015 Mar 1;133(3):326–332. doi: 10.1001/jamaophthalmol.2014.5265

Table 5. Changes in BiS Score of Patients With Infantile- or Childhood-Onset Esotropia vs Other Strabismus Subtypes After Strabismus Surgery.

Variable Improvement in BiS by ≥5 letters Indeterminate (Improvement or Worsening <5 Letters) Worsening of BiS by ≥5 Letters P Value for Fisher Exact Test
No. (% of Total) 95% CI No. (% of Total) 95% CI No. (% of Total) 95% CI
ETDRS .05
 Infantile- or childhood-onset esotropia 2 (10) (3-30) 13 (65) (41-81) 5 (25) (11-49)
 All other subtypes 17 (24) (15-35) 51(73) (61-82) 2 (3) (0.1-10)
2.5% LCA .24
 Infantile- or childhood-onset esotropia 2 (10) (3-31) 14 (70) (46-85) 4 (21) (9-43)
 All other subtypes 22 (31) (22-43) 39 (56) (43-67) 9 (13) (7-24)
1.25% LCA .15
 Infantile- or childhood-onset esotropia 4 (20) (9-43) 15 (75) (51-88) 1 (5) (1-24)
 All other subtypes 24 (34) (24-46) 34 (49) (36-60) 12 (17) (10-29)
ETDRS .11
 Intermittent exotropia 5 (23) (11-45) 17 (77) (55-89) 0
 All other subtypes 14 (20) (12-31) 47(69) (57-79) 7 (11) (5-21)
2.5% LCA .32
 Intermittent exotropia 8 (36) (21-59) 10 (45) (24-63) 4 (18) (8-40)
 All other subtypes 16 (23) (15-34) 43 (64) (51-74) 9 (13) (7-24)
1.25% LCA .007
 Intermittent exotropia 11 (50) (32-72) 6 (27) (11-45) 5 (23) (10-44
 All other subtypes 17 (24) (16-36) 43 (65) (51-74) 8 (12) (6-22)

Abbreviations: BiS, binocular summation; ETDRS, Early Treatment Diabetic Retinopathy Study; LCA, low-contrast acuity.