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. 2015 Jan 9;6(6):4080–4096. doi: 10.18632/oncotarget.2977

Figure 1. TRAF4 cytoplasmic expression correlates with activation of p70s6k and poor survival in breast cancer patients.

Figure 1

(A) Immunohistochemical analysis of TRAF4 and p-p70s6k(T389) localization in normal breast tissue (NBT) and breast cancer tissue (BCT). Bar, 20 μm. (B) The positive rate of p-p70s6k expression was positively correlated with cytoplasmic TRAF4 expression level in breast cancer patients (chi-square test, p = 0.004). Bar, 10 μm. (C) Kaplan-Meier analysis of overall survival curves of cytoplasmic TRAF4 expressions in 80 cases of breast cancer patients was shown. High Cytoplasm expression of TRAF4 significantly correlated with patient poor survival (log-rank test, p = 0.02).