Table 4. Cell growth inhibition studies in human melanoma cell lines.
Cell line | IC50 (μM) | |
---|---|---|
NBDHEX | MC3181 | |
A375 | 1.45 ± 0.14 | 2.31 ± 0.04 |
SK23-MEL | 1.19 ± 0.09 | 1.79 ± 0.05 |
G-361 | 0.55 ± 0.03 | 0.78 ± 0.04 |
MALME-3M | 1.80 ± 0.12 | 2.42 ± 0.16 |
IST-MEL-1 | 1.42 ± 0.05 | 0.92 ± 0.07 |
Cells were exposed to different concentrations (0.05–50 μM) of MC3181 or NBDHEX for 48 h. The IC50 values for each compound were then evaluated by the SRB assay