Figure 5. Both HDAC and HAT are involved in glycolysis induced histone acetylation.

The level of lactate (A), pyruvate (B), acetyl-CoA (C) or HDAC activity (D) in 2-DG treated (10 mM, 24 h) or control A549 cells was measured. Data shown are average values of three experiments with error bar indicate mean ± s.d.