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. 2015 Feb 24;6(6):4440–4450. doi: 10.18632/oncotarget.2913

Table 1. Demographics, etiology and biochemistry of liver disease and Child-Pugh class of patients.

Total 2002–2006 2007–2011 p
n (%) 2045 (100) 558 (27.3) 1487 (72.7)
Gender [male/female (%)] 1662/383 (81.3/18.7) 453/105 (81.2/18.8) 1209/278 (81.3/18.7) 0.950
Age (mean ± SD) 2045 (52.5 ± 12.1) 51.5 ± 12.5 53.0 ± 12.0 0.017
Etiology [n (%)] 2045 (100) 0.003
 HBV 1504 (73.5) 396 (71.0) 1108 (74.5) 0.106
 HCV 83 (4.1) 15 (2.7) 68 (4.6) 0.054
 HBV+HCV 17 (0.8) 2 (0.4) 15 (1.0) 0.242
 The others 441 (21.6) 145 (26.0) 296 (19.9) 0.003
ALT [n (%)] 2045 (100) 0.076
 ≤ 40 783 (38.3) 225 (40.3) 558 (37.5)
 40–200 1171 (57.3) 301 (53.9) 870 (58.5)
 >200 91 (4.4) 32 (5.7) 59 (4.0)
AST [n (%)] 2045 (100) 0.633
 ≤ 40 401 (19.6) 104 (18.6) 297 (20.0)
 40–200 1399 (68.4) 382 (68.5) 1017 (68.4)
 >200 245 (12.0) 72 (12.93) 173 (11.6)
Child-Pugh class [n (%)] 1843 (90.1) 0.587
 A 959 (52.0) 266 (53.8) 693 (51.4)
 B 771 (41.8) 197 (39.9) 574 (42.6)
 C 113 (6.1) 31 (6.3) 82 (6.1)

SD, standard deviation; HBV, hepatitis B virus; HCV, hepatitis C virus; ALT, alanine aminotransferase; AST, aspartate aminotransferase.