Table 4. Correlation analysis between methylated status of CpG sites of ZNF545 promoter and clinicopathological characteristics.

Variables	Methylated CpG sites ≥ 3	Methylated CpG −232	Methylated CpG −214	Methylated CpG −176	Methylated CpG −144	Methylated CpG −116
Gender
Male	60	48	53	54	51	46
Female	22	16	21	18	21	16
P value	0.511	0.348	0.849	0.298	0.989	0.462
Age at surgery (years)
≤ 60	42	31	36	33	34	26
> 60	40	33	38	39	38	36
P value	0.130	0.074	0.048	0.010	0.024	0.002
Tumor location
Upper third	25	23	21	22	23	18
Middle third	18	14	19	17	16	14
Lower third	35	25	31	30	29	27
≥ 2/3 stomach	4	2	3	3	4	3
P value	0.819	0.198	0.766	0.775	0.613	0.981
Tumor size (cm)
< 4.0	10	5	9	9	7	8
≥ 4.0	72	59	65	63	65	54
P value	0.090	0.011	0.123	0.161	0.024	0.261
Lauren classification
Intestinal	23	19	21	21	19	15
Diffuse	50	39	44	42	45	40
Mixed	9	6	9	9	8	7
P value	0.061	0.295	0.026	0.016	0.145	0.229
Depth of tumor invasion (T stage)
T1	0	0	0	0	0	0
T2	9	8	9	8	9	8
T3	51	39	45	44	42	38
T4	22	17	20	20	21	16
P value	0.452	0.669	0.551	0.513	0.381	0.701
Number of metastatic lymph nodes (N stage)
N0	16	12	14	14	15	11
N1	30	24	28	26	24	22
N2	17	17	17	17	17	15
N3	19	11	15	15	16	14
P value	0.096	0.989	0.594	0.633	0.385	0.505
Location of lymph node metastasis
No	16	12	14	14	15	11
Perigastric	31	22	28	27	28	25
Extragastric	35	30	32	31	29	26
P value	0.826	0.380	0.804	0.818	0.936	0.887