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Proangiogenic effects of hAMC-CM in vivo. Capillary density was assessed by isolectin B4 immunostaining (green) at both the border and the remote zone (n = 5 animals per group). Scale bar = 100 μm. ∗, p < .001 versus saline; †, p < .05 versus fib-CM. All data are expressed as the mean ± SD. Abbreviations: fib-CM, human dermal fibroblast conditioned medium; hAMC-CM, conditioned medium obtained from human amniotic membrane-derived mesenchymal stromal cells.
