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. 2015 Mar 17;16(1):195. doi: 10.1186/s12864-015-1364-0

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© Zhou et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Upstream regulators JunB and MEF2C. A. Transcription factor JunB is predicted to be activated in the high-FE chickens by Ingenuity Upstream Regulator Analysis with P-value = 1.20E-03 and Z-score = 2.425. B. MEF2C is predicted to be activated in the high-FE chickens with P-value = 3.11E-02 and Z-score = 2.186. Red and green nodes indicate genes up- and down-regulated in the high-FE chicken, respectively. The color intensity is proportional to the degree of fold change. The upstream regulators are colored with their predicted activation states: orange (activated). Edges connecting the nodes are colored with orange when upstream regulators have activating effects on their target genes.