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. 2015 Apr 29;10(4):e0124889. doi: 10.1371/journal.pone.0124889

Table 3. Hazard Ratios (HRs) and confidence intervals from Cox regression analysis.

  Unadjusted Adjusted a
  HR 95% CI p-value HR 95% CI p-value
DFI ITT 0.80 (0.54, 1.19) 0.274 0.80 (0.53, 1.20) 0.461
Adherence 0.79 (0.50, 1.23) 0.300 0.76 (0.48, 1.21) 0.252
OS b 1 year 1.01 (0.66, 1.54) 0.963 1.01 (0.64, 1.59) 0.961
2 years 1.40 (0.72, 2.75) 0.325 1.45 (0.70, 3.00) 0.316

aAdjusted for weight and gender (male, female).

bProportional hazards violated (p = 0.08 for OS ITT analysis, p<0.05 for all others).

ITT = Intent to treat