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. 2015 Apr 29;10(4):e0125201. doi: 10.1371/journal.pone.0125201

Fig 1. Schematic representation of the Computel algorithm for mean telomere length estimation.

Fig 1

Computel takes whole-genome NGS short-reads as input; maps them to the telomeric index built based on user-defined telomeric repeat pattern and the read length; and calculates the mean telomere length based on the ratio of telomeric and reference genome coverage, the number of chromosomes, and the read length.