Table 2. Genetic variability detected by the comparison among the casein genes transcripts in llama and the dromedary camel cDNAs reported by Kappeler et al.
CSN1S1 (αs1-casein) | CSN2 (β-casein) | CSN1S2 (αs2-casein) | CSN3 (κ-casein) | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Exon | Position | Llama | Dromedary | Exon | Position | Llama | Dromedary | Exon | Position | Llama | Dromedary | Exon | Position | Llama | Dromedary |
cDNAaa | LK999986 | AJ012628 | cDNAaa | LK999992 | AJ012630 | cDNAaa | LK999989 | AJ012629 | cDNAaa | LK999995 | Y10082 | ||||
1 | 51 | G | a | 1 | 45–46 | ga | — | 2 | 66–14 | AA G Lys | AA A Lys | 1 | 21 | a | g |
2 | 58 | c | t | 1 | 50–51 | aa | tt | 2 | 98–3 | GCTAla | GTTVal | 1 | 50 | g | a |
2 | 98–5 | GC C Ala | GG T Ala | 2 | 60 | t | g | 5 | 16821 | TTA Leu | TTT Phe | 3 | 135–14 | GT C Val | GT T Val |
4 | 16820 | CAGGln | GAGGlu | 2 | 90–7 | C T G Leu | C G G Arg | 6 | 22239 | ACG Thr | ACA Thr | 3 | 159–6 | CT G Leu | CT A Leu |
10 | 30766 | ACGThr | AAGLys | 3 | 1369 | GCG Ala | GCC Ala | 6 | 22841 | TGT Cys | TGC Cys | 5 | 20410 | TGC Cys | TGT Cys |
10 | 31067 | GTAVal | GAAGlu | 4 | 14613 | GTGVal | TTGLeu | 8 | 26654 | GTTVal | GCTAla | 5 | 20611 | TGTCys | TTTPhe |
10 | 32371 | AGC Ser | AGT Ser | 7 | 31067 | ATT Ile | ATC Ile | 9 | 35784 | GTT Val | GTG Val | 5 | 21614 | GTA Val | GTG Val |
12 | 396–39796 | ATTIle | TATTyr | 7 | 34378 | CCT Pro | CCG Pro | 9 | 36386 | AAT Asn | AAC Asn | 5 | 26430 | TTT Phe | TTC Phe |
15 | 482124 | AAA Lys | AAG Lys | 7 | 414102 | ATCIle | ACCThr | 9 | 38694 | ATGMet | AGGArg | 5 | 34858 | TAT Tyr | TAC Tyr |
15 | 483125 | TTGLeu | CTGLeu | 7 | 416103 | GTCVal | ATCIle | 9 | 38995 | GTCVal | GCCAla | 5 | 36062 | GCA Ala | GCC Ala |
19 | 604165 | CAAGln | CCAPro | 7 | 458117 | CTALeu | GTAVal | 13 | 501132 | GAG Glu | GAA Glu | 5 | 45092 | CGT Arg | CGC Arg |
19 | 690194 | CACHis | TACTyr | 7 | 545146 | CACHis | TACTyr | 17 | 719 | t | g | 5 | 506111 | ATCIle | AACAsn |
21 | 814 | a | - | 7 | 680191 | CTTLeu | GTTVal | 17 | 762 | a | g | 5 | 510112 | CCC Pro | CCT Pro |
21 | 821 | a | g | 7 | 701198 | ATAIle | GTAVal | 17 | 766–767 | ca | tg | 5 | 537121 | GAA Glu | GAG Glu |
21 | 838 | t | c | 7 | 745212 | CTC Leu | CTT Leu | 17 | 771 | g | a | 5 | 546124 | GTC Val | GTT Val |
21 | 842 | t | c | 9 | 826 | c | a | 17 | 777 | g | a | 5 | 558128 | GCT Ala | GCC Ala |
21 | 883 | a | g | 857 | t | c | 17 | 912/913 | - | t | 5 | 566131 | GTAVal | GCAAla | |
21 | 988 | a | c | 869 | g | a | 17 | 965 | g | a | 5 | 618148 | AGT Ser | AGC Ser | |
21 | 1172 | c | t | 871/872 | - | t | 5 | 651159 | TCA Ser | TCG Ser | |||||
882 | g | a | 5 | 678 | t | g | |||||||||
885 | g | a | 6 | 730 | t | c | |||||||||
892 | t | c | |||||||||||||
900 | c | t | |||||||||||||
972 | a | g | |||||||||||||
987 | t | g | |||||||||||||
990 | g | a | |||||||||||||
994 | c | t | |||||||||||||
1003 | t | c | |||||||||||||
1021 | a | g | |||||||||||||
1023 | g | t | |||||||||||||
1030/1031 | - | a | |||||||||||||
1045 | g | t | |||||||||||||
1065 | g | a | |||||||||||||
1089 | t | c |
Polymorphic nucleotides in the triplets are underlined, when they fall within the peptide leader they are also reported in Italics. Amino acid changes are showed in bold. Insertions/deletions are reported as dashes. Numbering is relative to the llamas cDNAs.