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. 2015 Apr 29;10(4):e0124963. doi: 10.1371/journal.pone.0124963

Table 2. Genetic variability detected by the comparison among the casein genes transcripts in llama and the dromedary camel cDNAs reported by Kappeler et al.

[15].

CSN1S1 (αs1-casein) CSN2 (β-casein) CSN1S2 (αs2-casein) CSN3 (κ-casein)
Exon Position Llama Dromedary Exon Position Llama Dromedary Exon Position Llama Dromedary Exon Position Llama Dromedary
cDNAaa LK999986 AJ012628 cDNAaa LK999992 AJ012630 cDNAaa LK999989 AJ012629 cDNAaa LK999995 Y10082
1 51 G a 1 45–46 ga 2 66–14 AA G Lys AA A Lys 1 21 a g
2 58 c t 1 50–51 aa tt 2 98–3 GCTAla GTTVal 1 50 g a
2 98–5 GC C Ala GG T Ala 2 60 t g 5 16821 TTA Leu TTT Phe 3 135–14 GT C Val GT T Val
4 16820 CAGGln GAGGlu 2 90–7 C T G Leu C G G Arg 6 22239 ACG Thr ACA Thr 3 159–6 CT G Leu CT A Leu
10 30766 ACGThr AAGLys 3 1369 GCG Ala GCC Ala 6 22841 TGT Cys TGC Cys 5 20410 TGC Cys TGT Cys
10 31067 GTAVal GAAGlu 4 14613 GTGVal TTGLeu 8 26654 GTTVal GCTAla 5 20611 TGTCys TTTPhe
10 32371 AGC Ser AGT Ser 7 31067 ATT Ile ATC Ile 9 35784 GTT Val GTG Val 5 21614 GTA Val GTG Val
12 396–39796 ATTIle TATTyr 7 34378 CCT Pro CCG Pro 9 36386 AAT Asn AAC Asn 5 26430 TTT Phe TTC Phe
15 482124 AAA Lys AAG Lys 7 414102 ATCIle ACCThr 9 38694 ATGMet AGGArg 5 34858 TAT Tyr TAC Tyr
15 483125 TTGLeu CTGLeu 7 416103 GTCVal ATCIle 9 38995 GTCVal GCCAla 5 36062 GCA Ala GCC Ala
19 604165 CAAGln CCAPro 7 458117 CTALeu GTAVal 13 501132 GAG Glu GAA Glu 5 45092 CGT Arg CGC Arg
19 690194 CACHis TACTyr 7 545146 CACHis TACTyr 17 719 t g 5 506111 ATCIle AACAsn
21 814 a - 7 680191 CTTLeu GTTVal 17 762 a g 5 510112 CCC Pro CCT Pro
21 821 a g 7 701198 ATAIle GTAVal 17 766–767 ca tg 5 537121 GAA Glu GAG Glu
21 838 t c 7 745212 CTC Leu CTT Leu 17 771 g a 5 546124 GTC Val GTT Val
21 842 t c 9 826 c a 17 777 g a 5 558128 GCT Ala GCC Ala
21 883 a g 857 t c 17 912/913 - t 5 566131 GTAVal GCAAla
21 988 a c 869 g a 17 965 g a 5 618148 AGT Ser AGC Ser
21 1172 c t 871/872 - t 5 651159 TCA Ser TCG Ser
882 g a 5 678 t g
885 g a 6 730 t c
892 t c
900 c t
972 a g
987 t g
990 g a
994 c t
1003 t c
1021 a g
1023 g t
1030/1031 - a
1045 g t
1065 g a
1089 t c

Polymorphic nucleotides in the triplets are underlined, when they fall within the peptide leader they are also reported in Italics. Amino acid changes are showed in bold. Insertions/deletions are reported as dashes. Numbering is relative to the llamas cDNAs.