Table 4.

Immunological and virological parameters at baseline in ISS T-002 and ISS OBS T-002 study participants

	ISS T-002		ISS OBS T-002		p-value b
	n	Mean ± s.d. a	n	Mean ± s.d. a
Phenotype (cells/μL)
CD4+	152	661 ± 231	79	700 ± 300	0.2671
CD8+	152	802 ± 393	79	881 ± 360	0.1295
B	152	241 ± 121	79	307 ± 164	0.0006
NK	152	232 ± 152	79	268 ± 193	0.1231
CD4 + subsets (%)
Naïve	94	31 ± 14	31	28 ± 13	0.7057
Effector memory	94	22 ± 12	31	20 ± 8	0.5304
Central memory	94	47 ± 10	31	51 ± 9	0.2810
CD8 + subsets (%)
Naïve	94	26 ± 11	31	30 ± 11	0.0835
Effector memory	94	52 ± 13	31	47 ± 13	0.0756
Central memory	94	22 ± 10	31	23 ± 9	0.7302
HIV DNA (log 10 copies/10 6 CD4 + cells)	142	3.1 ± 0.5	54	3.0 ± 0.5	0.4381
Tat 7.5 μg, 3x	36	3.1 ± 0.6
Tat 7.5 μg, 5x	36	3.0 ± 0.6
Tat 30 μg, 3x	36	3.2 ± 0.5
Tat 30 μg, 5x	34	3.0 ± 0.5

"n indicates the number of individuals evaluable for each parameter according to residual specimen availability, since they were part of second line laboratory testing".

^aStandard deviation; ^b t-test was applied.