. 2015 Apr 29;12:33. doi: 10.1186/s12977-015-0151-y

Table 5.

Baseline Immunological-virological parameters in ISS T-002 subjects pre- and post-protocol amendment and OBS subjects

	ISS T-002 pre-amendment		ISS T-002 post-amendment		ISS OBS T-002		OBS vs pre-amendment T-002	OBS vs post-amendment T-002
	n	Mean ± s.d. ^a	n	Mean ± s.d.	n	Mean ± s.d.	p-value ^b	p-value ^b
Phenotype (cells/μL)
CD4⁺	80	694 ± 236	72	624 ± 223	79	700 ± 300	0.8880	0.0755
CD8⁺	80	822 ± 344	72	780 ± 443	79	881 ± 360	0.2955	0.1299
B	80	232 ± 111	72	251 ± 132	79	307 ± 164	0.0009	0.0244
NK	80	237 ± 149	72	226 ± 159	79	268 ± 193	0.2596	0.1480
CD4 ⁺ subsets (%)
Naïve	21	32 ± 19	73	31 ± 12	31	28 ± 13	0.6337	0.7940
Effectors memory	21	23 ± 14	73	22 ± 12	31	20 ± 8	0.4377	0.6029
Central memory	21	45 ± 15	73	48 ± 9	31	51 ± 9	0.2314	0.3422
CD8 ⁺ subsets (%)
Naïve	21	26 ± 11	73	26 ± 12	31	30 ± 11	0.2004	0.0912
Effectors memory	21	53 ± 12	73	52 ± 14	31	47 ± 13	0.0683	0.1174
Central memory	21	20 ± 11	73	22 ± 10	31	23 ± 9	0.4262	0.9136
HIV DNA (log ₁₀ copies/10 ⁶ CD4 ⁺ cells	78	3.1 ± 0.5	64	3.1 ± 0.5	54	33.0 ± 0.5	0.4505	0.5276

"n indicates the number of individuals evaluable for each parameter according to residual specimen availability, since they were part of second line laboratory testing". ^aStandard deviation; ^b t-test was applied.