Table 1.

Baseline (CKD annual visit 2) characteristics of the overall cohort and those meeting each of the three PEW definitions. Children meeting each definition were compared to the overall cohort.

	Overall N=528	Minimal PEW	Standard PEW	Modified PEW
African-American	18%	22%	15%	23%
Female	39%	35%	26%	35%
Pre-Pubertal Status	48%	46%	57%	51%
Glomerular Diagnosis	21%	23%	15%	22%
Age (yr; median [IQR])	12 [8, 16]	12 [8, 16]	10 [6, 14]	12 [7, 16]
Height for age and sex z-score (median [IQR])	−0.7 [−1.4, −0.0]	−0.8 [−1.7, −0.1]	−0.7 [−1.7, 0.2]	−1.1 [−2.0, −0.2]
Weight for age and sex z-score (median [IQR])	−0.2 [−0.9, 0.7]	−0.5 [−1.3, 0.3]	−0.8 [−1.6, −0.1]	−0.7 [−1.6, 0.2]*
BMI for height-age and sex z-score (median [IQR])	0.5 [−0.3, 1.3]	0.1 [−0.5, 0.9]*	−0.4 [−0.7, −0.1]*	0.0 [−0.5, 0.8]*
Mid Upper Arm Circumference for height-age and sex z-score (median [IQR])	−0.8 [−3.3, 2.6]	−2.2 [−4.6, −0.5]*	−3.2 [−4.8, −1.4]*	−2.5 [−4.7, −0.7]*
Urine Protein to Creatinine Ratio (Upc)	0.5 [0.2, 1.2]	0.8 [0.2, 1.8]*	0.8 [0.2, 1.6]	0.8 [0.2, 1.8]
Upc>2.0	14%	24%*	18%	24%*
Anemia	39%	43%	32%	45%
Acidosis	32%	38%	28%	39%
Hypertension	48%	45%	41%	46%
Dyslipidemia	51%	54%	62%	57%
Low birth weight	19%	25%	27%	28%
Growth hormone use	13%	13%	13%	14%
ieGFR (median [IQR])	45 [33, 58]	42 [30, 56]	42 [31, 55]	43 [30, 56]
CKD Stage
Stage 1 or 2	23%	24%	22%	23%
Stage 3a	26%	19%	22%	20%
Stage 3b	31%	32%	30%	31%
Stage 4 or 5	20%	25%	25%	26%

^*indicates statistically significantly different from the overall cohort using an alpha level of 0.05