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. 2015 Apr 29;10(4):e0124116. doi: 10.1371/journal.pone.0124116

Table 8. One-Way Sensitivity Analyses on Cases Prevented, A U.S.-Perspective Savings, B and ICER C associated with Implementing Overseas TB Screening in Foreign-Born Student-Visa Applicants.

Parameter Outcome India China
Base Case Cases Prevented A 29.2 127.8
U.S. Savings B $458,696 $2,234,411
ICER C $15,063 $22,187
Suspected TB up 50% D Cases Prevented A 43.7 191.8
U.S. Savings B $688,046 $3,351,615
ICER C $6,330 $10,485
Suspected TBdown 50% D Cases Prevented A 14.5 64.0
U.S. Savings B $229,349 $1,117,205
ICER C $41,592 $57,188
0.3% Class B-1 students diagnosed with TB in U.S. E Cases Prevented A 29.2 127.8
U.S. Savings B $389,273 $2,107,871
ICER C $17,441 $23,159
3% of Class B-1 students diagnosed with TB in U.S. E Cases Prevented A 29.2 127.8
U.S. Savings B $482,996 $2,357,273
ICER C $14,231 $21,209
Undergraduate students hospitalized forfeit 100% tuition Cases Prevented A 29.2 127.8
U.S. Savings B $512,350 $2,449,564
ICER C $13,226 $20,504
Undergraduate students hospitalized forfeit 0% tuition Cases Prevented A 29.2 127.8
U.S. Savings B $333,504 $1,732,386
ICER C $19,351 $26,115
Graduate students hospitalized forfeit 70% tuition Cases Prevented A 29.2 127.8
U.S. Savings B $510,609 $2,442,585
ICER C $13,285 $20,558
Hospitalization costs up 50% Cases Prevented A 29.2 127.8
U.S. Savings B $623,067 $2,893,546
ICER C $9,434 $17,030
Hospitalization costs down 50% Cases Prevented A 29.2 127.8
U.S. Savings B $349,115 $1,794,987
ICER C $18,816 $25,626
Opportunity costs not included Cases Prevented A 29.2 127.8
U.S. Savings B $380,925 $1,885,690
ICER C $6,914 $13,260

ICER = Incremental Cost-Effectiveness Ratio; TB = Tuberculosis; U.S. = United States;

A-Cases prevented denotes cases prevented from being imported into the U.S. by active overseas screening programs;

B-U.S. perspective savings or costs represents the total projected costs or savings in the U.S. with overseas screening programs;

C-The incremental cost-effectiveness ratio is from the combined perspective which combines both overseas and foreign costs;

D-Suspected TB includes those with abnormal chest radiograph, signs and symptoms of TB, and/or known HIV infection;

E-Class B-1 indicates those who have an abnormal chest radiograph, signs and symptoms of TB, or known HIV infection during overseas screening and are encouraged to follow-up at U.S. PHD;