Table 3. Univariate and multivariable linear regression model predicting change in eGFR over one year follow-up.

	Univariate Model		Multivariable Model
Predictors of change in eGFR at one year (ml/min/1.73m2 difference from baseline)	β Coefficient (95% CI)	P value	β Coefficient (95% CI)	P value
Age, per 10 years	0.40 (-3.33, 4.20)	0.82	-0.64 (-5.12, 3.84)	0.77
Sex (male versus female)	-0.86 (-6.97,5.20)	0.78	2.5 (-3.48, 8.53)	0.4
Diabetes (versus non-diabetic)	-10.13 (-17.47, -2.79)	0.008	-6.09 (-13.45, 1.27)	0.1
Cirrhosis (versus non-cirrhotic)	-5.67 (-11.43, -0.99)	0.05	-4.21 (-10.58, 2.15)	0.19
HIV coinfection	4.46 (-3.90, 12.83)	0.29	5.19 (-3.42, 13.82)	0.23
Baseline eGFR, per 10ml/min increase	-2.19 (-3.72, -0.66)	0.006	-1.18 (-3.70, 0.15)	0.071
Significant creatinine rise during telaprevir	-6.65 (-29.74, -3.25)	0.02	-6.31 (-12.08, -0.53)	0.03

^{Abbreviations: HIV = human immunodeficiency virus, eGFR = estimated glomerular filtration rate}