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. 2015 Apr 29;10(4):e0122626. doi: 10.1371/journal.pone.0122626

Table 3. Unadjusted and adjusted Incidence Rate Ratios (95% CI) for opioid substitution treatment drug codes by age-band, deprivation and time period (1994–2012).

Demographics Unadjusted IRR(95% CI) *Adjusted IRR(95% CI)
Males Females Males Females
Age-band
16–24 1.38 (1.27–1.49) 0.89 (0.81–0.97) 1.22 (1.16–1.38) 0.78 (0.71–0.86)
25–34 2.72 (2.55–2.91) 1.39 (1.29–1.50) 1.84 (1.71–1.97) 0.86 (0.79–0.93)
35–44 1.82 (1.70–1.95) 1.16 (1.08–1.25) 1.58 (1.47–1.71) 0.79 (0.73–0.86)
45–64 1 1 1 1
Townsend Score
1 (least deprived) 1 1 1 1
2 1.40 (1.26–1.54) 1.34 (1.21–1.48) 1.37 (1.23–1.52) 1.31 (1.18–1.46)
3 2.07 (1.89–2.27) 1.66 (1.51–1.83) 1.98 (1.80–2.18) 1.59 (1.44–1.76)
4 3.10 (2.84–3.38) 2.29 (2.08–2.51) 2.75 (2.51–3.01) 2.08 (1.89–2.29)
5(most deprived) 4.86 (4.45–5.30) 3.01 (2.74–3.32) 3.92 (3.58–4.30) 2.55 (2.30–2.82)
Time periods
1994–2000 1.84 (1.71–1.97) 2.14 (1.97–2.32) 1.82 (1.69–1.97) 2.01 (1.84–2.19)
2001–2006 1.49 (1.41–1.58) 1.62 (1.52–1.73) 1.48 (1.39–1.57) 1.59 (1.49–1.71)
2006–2011 1 1 1 1

*Adjusted for age deprivation and time period