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. 2015 Apr 29;10(4):e0122626. doi: 10.1371/journal.pone.0122626

Table 4. Unadjusted and adjusted Incidence Rate Ratios (95% CI) for opioid substitution treatment Read codes by age-band, deprivation and time period (1994–2012).

Demographics Unadjusted IRR (95% CI) Adjusted IRR (95% CI)
Males Females Males Females
Age-band
16–24 4.46 (4.01–4.96) 5.94 (5.14–6.86) 4.64 (4.16–5.17) 4.85 (4.19–5.63)
25–34 10.3(9.40–11.31) 9.24(8.09–10.55) 7.87 (7.14–8.67) 5.09 (4.43–5.84)
35–44 5.39 (4.89–5.95) 4.05 (3.50–4.68) 3.79 (3.42–4.20) 2.49 (2.15–2.90)
45–64 1 1 1 1
Townsend Score
1 (least deprived) 1 1 1 1
2 1.74 (1.52–1.99) 1.64 (1.34–2.01) 1.69 (1.48–1.94) 1.57 (1.28–1.92)
3 3.03 (2.67–3.42) 3.42 (2.86–4.08) 2.72 (2.40–3.08) 2.97 (2.48–3.55)
4 5.89 (5.25–6.61) 6.11 (5.16–7.24) 4.66 (4.15–5.24) 4.59 (3.88–5.44)
5(most deprived) 11.2(10.0–12.6) 10.9(9.19–12.8) 8.21 (7.33–9.20) 7.51 (6.35–8.88)
Time
1994–2000 2.11 (1.94–2.30) 2.33 (2.05–2.65) 2.09 (1.91–2.28) 2.09 (1.91–2.28)
2001–2006 1.51 (1.43–1.61) 1.81 (1.66–1.97) 1.49 (1.39–1.58) 1.49 (1.39–1.58)
2006–2011 1 1 1 1

*Adjusted for age deprivation and time period