Table 1. Baseline clinical characteristics.
| Characteristics (Unit) | eGFR (mL/min/1.73 m2) | P values | |||
|---|---|---|---|---|---|
| Overall (n=66) | <30 (n=17) | 30-59 (n=26) | 60-89 (n=23) | ||
| Age (yr) | 66.9 ± 15.0 | 68.4 ± 13.4 | 72.1 ± 8.7 | 59.9 ± 19.1 | 0.014 |
| Male | 40 (58.0) | 10 (58.8) | 17 (65.4) | 13 (56.5) | 0.806 |
| Resting heart rate (beats/min) | 95.0 ± 28.5 | 91.7 ± 33.3 | 97.2 ± 25.1 | 95.0 ± 29.5 | 0.833 |
| Mean blood pressure (mmHg) | 98.9 ± 24.8 | 103.4 ± 23.3 | 92.6 ± 22.1 | 102.8 ± 28.1 | 0.251 |
| Body mass index (kg/m2) | 23.0 ± 3.5 | 22.1 ± 2.7 | 23.4 ± 3.7 | 23.1 ± 4.0 | 0.491 |
| NYHA functional class ≥ III | 48 (72.7) | 12 (70.6) | 22 (84.6) | 14 (60.9) | 0.960 |
| Diabetes | 28 (42.4) | 9 (52.9) | 15 (57.7) | 4 (17.4) | 0.010 |
| Hypertension | 38 (57.6) | 12 (70.6) | 14 (53.8) | 12 (52.2) | 0.449 |
| Atrial fibrillation | 21 (31.8) | 7 (41.2) | 9 (34.6) | 5 (21.7) | 0.395 |
| Dyslipidemia | 22 (33.3) | 9 (52.9) | 6 (23.1) | 7 (30.4) | 0.119 |
| Ischemic etiology | 23 (34.8) | 9 (52.9) | 10 (38.5) | 4 (17.4) | 0.058 |
| Dilated cardiomyopathy | 32 (48.5) | 5 (29.4) | 14 (53.8) | 13 (56.5) | 0.185 |
| LV ESD (mm) | 51.1 ± 10.1 | 49.4 ± 7.5 | 51.4 ± 9.9 | 52.1 ± 12.2 | 0.703 |
| LV EDD (mm) | 60.5 ± 8.9 | 60.4 ± 6.7 | 60.0 ± 9.1 | 61.3 ± 10.4 | 0.885 |
| LV EF (%) | 27.5 ± 8.8 | 30.4 ± 8.0 | 26.1 ± 7.4 | 27.0 ± 10.5 | 0.271 |
| Serum creatinine (mg/dL) | 1.96 ± 1.45 | 3.98 ± 1.46 | 1.58 ± 0.36 | 0.91 ± 0.18 | < 0.001 |
| Serum BUN (mg/dL) | 37.7 ± 24.5 | 65.8 ± 27.0 | 35.5 ± 14.1 | 19.4 ± 7.1 | < 0.001 |
| Serum sodium (mM/L) | 136.5 ± 5.7 | 137.0 ± 5.6 | 136.4 ± 5.6 | 136.2 ± 6.2 | 0.912 |
| Hemoglobin (g/dL) | 12.3 ± 2.7 | 10.8 ± 2.7 | 12.3 ± 2.4 | 13.4 ± 2.5 | 0.006 |
| Renin-angiotensin antagonist | 44 (66.7) | 9 (52.9) | 20 (76.9) | 15 (65.2) | 0.260 |
| β blocker | 29 (43.9) | 11 (64.7) | 11 (42.3) | 7 (30.4) | 0.095 |
| Aldosterone antagonist | 9 (13.6) | 1 (5.9) | 5 (19.2) | 3 (13.0) | 0.457 |
Values represent the number (percentages) or mean±standard deviation.eGFR, estimated glomerular filtration rate;NYHA, New York Heart Association; LV ESD/EDD, left ventricular end-systolic/diastolic dimension; EF, Ejection fraction; BUN, Blood urea nitrogen.