Table 3. The area under curves of ST2 and BNP at admission and at discharge to predict death or heart failure readmission within 3 months after hospital discharge.
Variables | All patients (n=66) | Mild renal insufficiency (n=23) | Moderate renal insufficiency (n=26) | Severe renal insufficiency (n=17) | ||||
---|---|---|---|---|---|---|---|---|
AUC (95% CI) | P | AUC (95% CI) | P | AUC (95% CI) | P | AUC (95% CI) | P | |
sST at admission | 0.680 (0.539-0.821) | 0.024 | 0.825 (0.589-1.000) | 0.077 | 0.667 (0.428-0.905) | 0.169 | 0.614 (0.340-0.888) | 0.435 |
sST at discharge | 0.761 (0.641-0.882) | 0.001 | 0.965 (0.887-1.000) | 0.011 | 0.778 (0.594-0.961) | 0.022 | 0.629 (0.358-0.899) | 0.380 |
BNP at admission | 0.600 (0.445-0.754) | 0.210 | 0.456 (0.132-0.781) | 0.811 | 0.703 (0.501-0.904) | 0.095 | 0.543 (0.213-0.872) | 0.770 |
BNP at discharge | 0.747 (0.627-0.867) | 0.002 | 0.825 (0.636-1.000) | 0.077 | 0.732 (0.535-0.929) | 0.056 | 0.586 (0.296-0.875) | 0.558 |
Delta-sST2 | 0.549 (0.381-0.717) | 0.535 | 0.333 (0.000-0.867) | 0.363 | 0.565 (0.313-0.817) | 0.590 | 0.564 (0.283-0.846) | 0.661 |
Delta-BNP | 0.481 (0.316-0.645) | 0.806 | 0.246 (0.000-0.515) | 0.165 | 0.614 (0.385-0.844) | 0.346 | 0.457 (0.141-0.773) | 0.770 |
AUC, Area under curve; CI,Confidence interval; Delta-sST2, sST2 at admission minus sST2 at discharge; Delta-BNP, BNP at admission minus BNP at discharge.